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Otrivin Metered Dose Nasal Spray 0.05% is used for the treatment of of colds, it contains 0.5 mg of Xylometazoline hydrochloride in each mL. 1 spray puff corresponds to 0.035 mg of Xylometazoline hydrochloride. It is designed to be applied into the nostrils, where it exerts vasoconstricting effect thereby decongesting the mucosa of the nose and throat.