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Olfen 75 is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain in conditions like migraine headache, osteoarthritis or rheumatoid arthritis, ankylosing spondylitis and menstrual cramps. Olfen may also cause or worsen stomach or intestinal bleeding as in peptic ulcer disease. Taking olfen during the last 3 months of pregnancy may also harm the unborn baby. Do not breast-feed while taking olfen.